What is the difference between tolerance and addiction (be specific)? What is t

What is the difference between tolerance and addiction (be specific)?
What is the relationship between drug dose and drug potency (be specific)?
Why is the route of administration (swallowing, injection, etc.) an important issue (be specific and give times)?
What is meant by drug metabolism and excretion?
What are neurotransmitters, and how are they associated with drug use?
Why are non-narcotic analgesics (such as Aspirin, Tylenol, Motrin, etc.) necessary in the drug treatment field?
Describe precisely the way that a signal crosses the synaptic gap.
Name and describe the effects of three different neurotransmitters.